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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CCNE1
All Species:
34.24
Human Site:
S344
Identified Species:
57.95
UniProt:
P24864
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P24864
NP_001229.1
410
47077
S344
V
I
R
E
T
G
S
S
K
L
K
H
F
R
G
Chimpanzee
Pan troglodytes
XP_512559
393
44800
S326
V
I
R
E
T
G
S
S
K
L
K
H
F
R
G
Rhesus Macaque
Macaca mulatta
XP_001084995
410
47103
S344
V
I
R
E
T
G
S
S
K
L
K
H
F
R
G
Dog
Lupus familis
XP_541724
456
51105
S390
V
I
R
E
T
G
S
S
K
L
K
H
F
R
G
Cat
Felis silvestris
Mouse
Mus musculus
Q61457
408
46968
S342
V
I
R
E
M
G
S
S
K
L
K
H
F
R
G
Rat
Rattus norvegicus
P39949
411
47463
S345
V
I
R
E
M
G
S
S
K
L
K
H
F
R
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507249
405
46635
V336
M
V
P
F
V
K
V
V
R
G
A
A
P
V
K
Chicken
Gallus gallus
P49707
407
46720
S341
A
I
R
E
V
G
S
S
K
L
K
H
F
R
G
Frog
Xenopus laevis
Q91780
408
47153
S343
A
I
K
E
G
G
K
S
K
L
N
F
F
K
G
Zebra Danio
Brachydanio rerio
P47794
410
46612
S346
S
I
R
E
A
G
S
S
A
L
K
T
F
K
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54733
709
77202
L578
I
S
Q
K
A
P
Y
L
Q
L
N
E
Q
N
E
Honey Bee
Apis mellifera
XP_394802
457
51232
T362
C
L
L
R
S
A
I
T
P
V
E
S
H
S
G
Nematode Worm
Caenorhab. elegans
O01501
524
60567
K453
F
M
Q
A
Q
L
E
K
V
I
E
Y
V
E
P
Sea Urchin
Strong. purpuratus
XP_785047
424
48468
A359
T
I
R
E
V
G
V
A
Q
L
K
N
F
K
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.3
98.2
73.9
N.A.
78.7
79.5
N.A.
49
71.9
60.2
58.2
N.A.
28.2
38.2
24.2
44.5
Protein Similarity:
100
95.3
98.5
81.1
N.A.
88.7
90
N.A.
66.5
85.1
76.8
73.9
N.A.
39.6
55.1
41.4
60.8
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
0
86.6
53.3
66.6
N.A.
6.6
6.6
0
46.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
20
86.6
66.6
73.3
N.A.
33.3
40
33.3
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
0
0
8
15
8
0
8
8
0
8
8
0
0
0
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
72
0
0
8
0
0
0
15
8
0
8
8
% E
% Phe:
8
0
0
8
0
0
0
0
0
0
0
8
72
0
0
% F
% Gly:
0
0
0
0
8
72
0
0
0
8
0
0
0
0
72
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
50
8
0
0
% H
% Ile:
8
72
0
0
0
0
8
0
0
8
0
0
0
0
0
% I
% Lys:
0
0
8
8
0
8
8
8
58
0
65
0
0
22
8
% K
% Leu:
0
8
8
0
0
8
0
8
0
79
0
0
0
0
0
% L
% Met:
8
8
0
0
15
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
15
8
0
8
8
% N
% Pro:
0
0
8
0
0
8
0
0
8
0
0
0
8
0
8
% P
% Gln:
0
0
15
0
8
0
0
0
15
0
0
0
8
0
0
% Q
% Arg:
0
0
65
8
0
0
0
0
8
0
0
0
0
50
0
% R
% Ser:
8
8
0
0
8
0
58
65
0
0
0
8
0
8
0
% S
% Thr:
8
0
0
0
29
0
0
8
0
0
0
8
0
0
0
% T
% Val:
43
8
0
0
22
0
15
8
8
8
0
0
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _